Sciatic nerve pain can make it difficult to go about your normal daily activities. This nerve originates in the lower back and runs through the buttocks and down the legs, often causing pain or numbness in the legs, hips, feet and toes. It can be caused by bulging or ruptured discs, spinal stenosis, sciatica or piriformis syndrome, but there are also other causes of sciatic nerve pain that may be caused by problems like inflammation or herniated discs.
What are exosomes?
Exosomes are small vesicles that are released by cells and contain a wide range of molecules. These include proteins, nucleic acids, lipids, and other biomolecules. They have been linked to numerous human diseases such as cancer, Parkinson’s disease, Alzheimer’s disease and many others. But how do exosomes relate to the treatment of sciatic nerve pain?
What is sciatic nerve pain?
Sciatic nerve pain is the pain and discomfort that radiates down the back of your leg when a nerve in your spine is irritated. The sciatic nerve is a large bundle of nerve roots that connect to the spinal cord, running from the lower spine through the buttock and into each leg. Sciatica refers to pain along this nerve pathway caused by pressure or irritation on the sciatic nerve as it exits from each side of your lower spine. Typically, sciatica affects one leg more than the other and may be accompanied by numbness, tingling, or weakness in one or both legs. If left untreated, sciatica may become chronic and lead to permanent disability because you’ll lose mobility in one or both legs.
How can exosomes treat sciatic nerve pain?
There are a few ways that exosomes might provide relief for this type of pain. One way is by delivering therapeutic molecules to the site of injury to aid in repair, such as growth factors and antibodies. Exosomes can also activate autologous regulatory T cells (which suppress the immune system) or inhibit proinflammatory cytokines (proteins that can cause inflammation). They may also help with nerve regeneration by delivering neurotrophic factors (proteins which stimulate nerve growth and survival). In one study, small doses of human neural progenitor cells delivered via exosomes were injected into rats with chronic lumbar radicular pain caused by compression of their sciatic nerve. After treatment, the rat’s pain intensity was significantly reduced and the time it took them to right themselves after being placed on their side was shortened.
Where can I get exosome therapy for sciatic nerve pain?
The Remedy Health + Wellness located in Ft Lauderdale, FL is happy to offer its private health care clients exosome therapy to help alleviate that pain caused by sciatic nerve pain. Schedule and appointment today by clicking here.
Content Writer: John Annunziata / The Remedy Health + Wellness
